Phase I Clinical Trial (Noun)
Meaning
A clinical trial on a few persons to determine the safety of a new drug or invasive medical device; for drugs, dosage or toxicity limits should be obtained.
Classification
Nouns denoting acts or actions.
Examples
- Clinical trials are broken into four phases, and a Phase I clinical trial is the first phase in the testing of a new medication or treatment.
- The Phase I clinical trial evaluates the safety, tolerability, pharmacokinetics, and pharmacodynamics of a drug.
- A Phase I clinical trial has a small number of participants, usually just 20 to 80 people, to minimize the risks.
- The Phase I clinical trial is primarily concerned with assessing the safety of a drug or device in human subjects.
- Biotechnology firms often conduct Phase I clinical trials to determine whether a product may be suitable for further testing in later phases.