Phase I (Noun)
Meaning
A clinical trial on a few persons to determine the safety of a new drug or invasive medical device; for drugs, dosage or toxicity limits should be obtained.
Classification
Nouns denoting acts or actions.
Examples
- The researchers carefully monitored the patients during the Phase I clinical trial to assess the new medication's safety and efficacy.
- In a Phase I study, the device was tested on a small group of volunteers to identify potential side effects and determine proper usage guidelines.
- The pharmaceutical company initiated a Phase I clinical trial to evaluate the safety and pharmacokinetics of the novel compound in healthy subjects.
- Due to the invasive nature of the device, the Phase I trial was conducted with extreme caution and close observation of the participating subjects.
- Regulatory agencies review Phase I data to ensure that the benefits of proceeding to larger trials outweigh the risks associated with the experimental product.