Factor Xiii (Noun)
Meaning
In the clotting of blood thrombin catalyzes factor XIII into its active form (fibrinase) which causes fibrin to form a stable clot.
Classification
Nouns denoting substances.
Examples
- Factor XIII is an enzyme that plays a crucial role in the coagulation cascade, specifically in the stabilization of blood clots.
- Thrombin activates factor XIII, which then cross-links fibrin molecules to form a stable clot.
- In the absence of factor XIII, blood clots are more susceptible to fibrinolysis and may not form properly.
- Factor XIII deficiency is a rare bleeding disorder that can lead to impaired wound healing and increased risk of bleeding complications.
- The activation of factor XIII by thrombin is a critical step in the formation of a stable fibrin clot that can withstand mechanical stress.