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Antagonist (Noun)

A drug that neutralizes or counteracts the effects of another drug.

Nouns denoting man-made objects.

Someone who offers opposition.

Nouns denoting people.

The company's CEO was a major antagonist to the proposed merger, claiming it would lead to job losses and decreased profits.
In the debate, the opposing candidate served as a strong antagonist to the incumbent senator's views on taxation.
The environmental group has long been an antagonist to the logging company, which they accuse of destroying habitats.
As a vocal critic of the government's policies, the journalist had become an antagonist to the administration.
The union leader was a fierce antagonist to the company's plan to outsource jobs overseas.