Agonist (Noun)
Meaning 1
The principal character in a work of fiction.
Classification
Nouns denoting people.
Examples
- The novel's agonist, a young and ambitious lawyer, must navigate a complex web of corruption and deceit to uncover the truth.
- In the movie, the protagonist is often referred to as the agonist, but technically, the antagonist drives the plot forward, making them the true agonist.
- The tragic agonist of the play, a king with a fatal flaw, ultimately brings about his own downfall through a series of poor decisions.
- Throughout the story, the reader is drawn into the world of the agonist, a charismatic thief with a heart of gold.
- In classical Greek tragedy, the agonist is typically a noble or aristocratic character whose flaws lead to their own demise, as seen in the character of Oedipus.
Synonyms
Hypernyms
Hyponyms
Related Words
Meaning 2
(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction.
Classification
Nouns denoting man-made objects.
Examples
- Insulin is an agonist that binds to insulin receptors on the surface of cells, triggering a cascade of signals that regulate glucose uptake and metabolism.
- The beta-2 agonist albuterol is used to treat asthma by relaxing airway smooth muscles and increasing airflow to the lungs.
- Endorphins are natural agonists that bind to opioid receptors in the brain, producing feelings of pain relief and relaxation.
- The development of new 5-HT1A agonists has shown promise in the treatment of depression and anxiety disorders by modulating serotonin signaling.
- Adrenaline is a potent agonist that activates adrenergic receptors on various cells, triggering the body's "fight or flight" response by increasing heart rate, blood pressure, and energy mobilization.
Meaning 3
A muscle that contracts while another relaxes; "when bending the elbow the biceps are the agonist".
Classification
Nouns denoting body parts.
Examples
- The quadriceps muscle is the agonist when straightening the knee, while the hamstrings are the antagonist.
- When flexing the wrist, the flexor carpi radialis muscle acts as the agonist, contracting to pull the wrist downward.
- The pectoralis major muscle is the primary agonist when performing a push-up, as it contracts to move the arm.
- The gastrocnemius muscle is an agonist when pointing the foot, working in conjunction with the soleus muscle to flex the foot downward.
- When rotating the hip outward, the gluteus medius muscle acts as the agonist, contracting to move the leg away from the body.
Meaning 4
Someone involved in a contest or battle (as in an agon).
Classification
Nouns denoting people.
Examples
- The protagonist and antagonist clashed in the final showdown, each determined to emerge victorious as the ultimate agonist in the epic struggle.
- In the Greek myth, Hercules was the agonist who fought against the monstrous Hydra and won.
- The agonist in the chess tournament was a young prodigy who checkmated her opponent in a stunning upset.
- The wrestler's opponent was a formidable agonist who pushed him to his limits in the intense match.
- In the novel, the brave knight was the agonist who battled against the dark sorcerer to save the kingdom.