X-scid (Noun)
Meaning
SCID in male children resulting from mutation of a gene that codes for a protein on the surface of T cells that allows them to develop a growth factor receptor.
Classification
Nouns denoting natural processes.
Examples
- X-SCID is a severe immunodeficiency disorder that primarily affects male children due to the mutation of the IL2RG gene.
- The mutation that causes X-SCID disrupts the function of the common gamma chain, a protein necessary for T cell development.
- Male children with X-SCID often experience severe and recurrent infections due to their compromised immune systems.
- X-SCID is typically inherited in an X-linked recessive pattern, meaning the mutated gene is located on the X chromosome.
- The symptoms of X-SCID usually appear within the first few months of life, and without treatment, the condition is often fatal.