Vicissitude (Noun)
Meaning 1
Mutability in life or nature (especially successive alternation from one condition to another).
Classification
Nouns denoting attributes of people and objects.
Hypernyms
Meaning 2
A variation in circumstances or fortune at different times in your life or in the development of something; "the project was subject to the usual vicissitudes of exploratory research".
Classification
Nouns denoting natural events.