Urokinase (Noun)
Meaning
Protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis.
Classification
Nouns denoting substances.
Examples
- Urokinase is a protease produced by the kidneys that helps to break down blood clots by activating plasminogen to form plasmin.
- The doctor prescribed urokinase to treat the patient's pulmonary embolism by dissolving the blood clot in the lungs.
- Urokinase initiates fibrinolysis by converting plasminogen to plasmin, which then breaks down the fibrin matrix of blood clots.
- The researcher studied the role of urokinase in the development of vascular diseases, such as atherosclerosis and thrombosis.
- Urokinase can be administered intravenously or intra-arterially to treat acute ischemic strokes by rapidly dissolving blood clots in the brain.