Tumor Suppressor Gene (Noun)
Meaning
A suppressor gene that blocks unscheduled cell division.
Classification
Nouns denoting body parts.
Examples
- The TP53 gene is an example of a tumor suppressor gene that can prevent cancer formation by arresting the cell cycle when DNA damage occurs.
- Tumor suppressor genes such as RB1 help prevent the uncontrolled growth of cells in the body.
- Loss of function in a tumor suppressor gene like BRCA2 can significantly increase the risk of certain cancers, including breast cancer.
- When a tumor suppressor gene is mutated, it can lose its ability to regulate cell division and prevent cancer.
- The p21 tumor suppressor gene plays a crucial role in inhibiting cell proliferation by stopping cells from entering the S phase of the cell cycle.