Thiamine Pyrophosphate (Noun)
Meaning
A coenzyme important in respiration in the Krebs cycle.
Classification
Nouns denoting substances.
Examples
- Thiamine pyrophosphate is a coenzyme that plays a crucial role in the Krebs cycle by facilitating the conversion of pyruvate to acetyl-CoA.
- The enzyme alpha-ketoglutarate dehydrogenase relies on thiamine pyrophosphate as a coenzyme to catalyze the conversion of alpha-ketoglutarate to succinyl-CoA in the Krebs cycle.
- Thiamine pyrophosphate is essential for the proper functioning of the Krebs cycle, as it enables the transfer of acyl groups during the conversion of pyruvate to acetyl-CoA.
- In the Krebs cycle, thiamine pyrophosphate acts as a coenzyme for the enzyme pyruvate dehydrogenase, facilitating the conversion of pyruvate to acetyl-CoA.
- The coenzyme thiamine pyrophosphate is necessary for the decarboxylation reactions that occur in the Krebs cycle, allowing for the efficient production of ATP.