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Sabin Vaccine (Noun)

Meaning

An oral vaccine (containing live but weakened poliovirus) that is given to provide immunity to poliomyelitis.

Classification

Nouns denoting man-made objects.

Examples

  • The Sabin vaccine was the primary tool used to nearly eradicate polio worldwide by inducing mucosal immunity in the gut, where the virus primarily resides.
  • Oral administration of the Sabin vaccine allows it to grow in the gut, thereby providing immunity against future infections.
  • Researchers believed that the Sabin vaccine was crucial for eradicating poliomyelitis, as it was easier to administer than the inactivated poliovirus vaccine developed by Jonas Salk.
  • The Sabin vaccine has been most effective in immunizing vulnerable children in underdeveloped countries where sanitation is poor.
  • Inadequate cold chain storage and handling can render the Sabin vaccine ineffective or even harmful, leading to potential vaccine-derived poliovirus infections.

Synonyms

  • Oral Poliovirus Vaccine
  • TOPV
  • OPV
  • Trivalent Live Oral Poliomyelitis Vaccine
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