Sabin Vaccine (Noun)
Meaning
An oral vaccine (containing live but weakened poliovirus) that is given to provide immunity to poliomyelitis.
Classification
Nouns denoting man-made objects.
Examples
- The Sabin vaccine was the primary tool used to nearly eradicate polio worldwide by inducing mucosal immunity in the gut, where the virus primarily resides.
- Oral administration of the Sabin vaccine allows it to grow in the gut, thereby providing immunity against future infections.
- Researchers believed that the Sabin vaccine was crucial for eradicating poliomyelitis, as it was easier to administer than the inactivated poliovirus vaccine developed by Jonas Salk.
- The Sabin vaccine has been most effective in immunizing vulnerable children in underdeveloped countries where sanitation is poor.
- Inadequate cold chain storage and handling can render the Sabin vaccine ineffective or even harmful, leading to potential vaccine-derived poliovirus infections.