Protirelin (Noun)
Meaning
Hormone released by the hypothalamus that controls the release of thyroid-stimulating hormone from the anterior pituitary.
Classification
Nouns denoting substances.
Examples
- The hypothalamic peptide protirelin is a key regulator of thyroid function, as it stimulates the release of thyroid-stimulating hormone from the anterior pituitary gland.
- Protirelin secretion is influenced by various factors, including plasma levels of thyroid hormones, which provide feedback to the hypothalamus to regulate its release.
- In response to cold stress, the hypothalamus releases protirelin, which in turn stimulates the anterior pituitary to release thyroid-stimulating hormone, leading to increased thyroid hormone production.
- The pulsatile release of protirelin from the hypothalamus is essential for maintaining normal thyroid function, as it ensures the periodic release of thyroid-stimulating hormone from the anterior pituitary gland.
- Dysregulation of protirelin secretion has been implicated in various thyroid disorders, including hypothyroidism and hyperthyroidism, highlighting the importance of this hormone in maintaining thyroid homeostasis.