Prothrombinase (Noun)
Meaning
Coagulation factor that is converted to an enzyme that converts prothrombin to thrombin in a reaction that depends on calcium ions and other coagulation factors.
Classification
Nouns denoting substances.
Examples
- Prothrombinase is a coagulation factor complex that is converted to an enzyme that converts prothrombin to thrombin in a reaction that depends on calcium ions and other coagulation factors.
- The prothrombinase complex is crucial for the coagulation cascade, as it facilitates the conversion of prothrombin to thrombin in the presence of calcium ions.
- Formation of the prothrombinase complex involves the assembly of several coagulation factors, which come together to facilitate the conversion of prothrombin to thrombin.
- Research has shown that the prothrombinase complex plays a critical role in hemostasis, as disruptions in this complex can lead to bleeding disorders.
- The generation of prothrombinase is influenced by a number of coagulation factors, including tissue factor, factor VIIa, and calcium ions, which all contribute to its activation.