Proteolysis (Noun)
Meaning
The hydrolysis of proteins into peptides and amino acids by cleavage of their peptide bonds.
Classification
Nouns denoting natural processes.
Examples
- Proteolysis occurs in various cellular processes, including cell signaling pathways and the turnover of damaged or abnormal proteins.
- The disorder results from a defect in a specific enzyme involved in proteolysis, leading to an accumulation of unprocessed proteins.
- Proteolysis can be categorized as either endoproteolysis or exoproteolysis, depending on the location of the protein cleavage.
- Caspases are key regulators of apoptosis and work through the controlled process of proteolysis.
- The impaired regulation of proteolysis is associated with various diseases, including cancer, neurodegenerative disorders, and atherosclerosis.