Proaccelerin (Noun)
Meaning
A coagulation factor.
Classification
Nouns denoting substances.
Examples
- Proaccelerin, also known as factor V, is a vitamin K-dependent coagulation protein that plays a crucial role in blood clotting.
- Proaccelerin is converted to its active form during the coagulation cascade, where it works as a cofactor for the prothrombinase complex.
- Deficiency or dysfunction of proaccelerin is associated with bleeding disorders, such as factor V deficiency.
- In vitro, the addition of proaccelerin to plasma accelerates thrombin production and improves clotting times.
- Factor V, or proaccelerin, is produced in the liver and is an essential component of the extrinsic coagulation pathway.