Polygenic Disorder (Noun)
Meaning
An inherited disease controlled by several genes at once.
Classification
Nouns denoting natural processes.
Examples
- Type 2 diabetes is a classic example of a polygenic disorder, controlled by multiple genes that regulate insulin sensitivity and glucose metabolism.
- Schizophrenia is a complex polygenic disorder that arises from the interaction of several genes and environmental factors.
- Research has identified numerous genetic variants contributing to the risk of developing Alzheimer's disease, a polygenic disorder that affects millions worldwide.
- Huntington's disease is a polygenic disorder caused by the combined effect of mutations in the huntingtin gene and other genetic modifiers.
- Although the exact genetic mechanisms are not fully understood, coronary artery disease is believed to be a polygenic disorder influenced by multiple genetic variants.