Megaloblast (Noun)
Meaning
Abnormally large red blood cell present in pernicious anemia and folic acid deficiency.
Classification
Nouns denoting body parts.
Examples
- A megaloblast is typically found in the bone marrow of individuals with vitamin B12 deficiency or folic acid deficiency.
- The megaloblast seen in the patient's blood smear indicated a severe case of pernicious anemia.
- Megaloblasts are frequently observed in patients with untreated or undiagnosed celiac disease due to malabsorption of essential nutrients.
- Pernicious anemia is characterized by the presence of large numbers of megaloblasts in the bone marrow, indicating impaired erythropoiesis.
- The hematologist identified several megaloblasts in the bone marrow biopsy, consistent with a diagnosis of megaloblastic anemia.