Limb-girdle Muscular Dystrophy (Noun)
Meaning
An autosomal recessive form of muscular dystrophy that appears anywhere from late childhood to middle age; characterized by progressive muscular weakness beginning either in the shoulder or pelvic girdle; usually progresses slowly with cardiopulmonary complications in the later stages.
Classification
Nouns denoting natural processes.
Examples
- Limb-girdle muscular dystrophy is a rare genetic disorder that affects the muscles closest to the shoulders and hips, leading to progressive weakness and degeneration.
- The patient was diagnosed with limb-girdle muscular dystrophy at the age of 25, after experiencing muscle weakness and fatigue in her shoulder girdle for several years.
- Researchers are working to identify the genetic mutations responsible for limb-girdle muscular dystrophy, in the hopes of developing more effective treatments for the disease.
- Symptoms of limb-girdle muscular dystrophy can vary widely from person to person, but typically include progressive muscle weakness and wasting in the shoulder or pelvic girdle.
- Limb-girdle muscular dystrophy is often misdiagnosed as other muscular dystrophies, such as Duchenne or Becker muscular dystrophy, due to the similarity of symptoms and the lack of a clear diagnostic test.