Klinefelter's Syndrome (Noun)
Meaning
Syndrome in males that is characterized by small testes and long legs and enlarged breasts and reduced sperm production and mental retardation; a genetic defect in which an extra X chromosome (XXY) is present in the male.
Classification
Nouns denoting natural processes.
Examples
- Klinefelter's Syndrome affects about one in every 600 males and is a leading cause of infertility.
- Men with Klinefelter's Syndrome often have their testicles removed because of a higher risk of developing testicular cancer.
- Klinefelter's Syndrome is usually diagnosed accidentally when an adult male undergoes a semen analysis as part of an infertility investigation.
- Tall stature, long limbs, and sparse body hair are typical features of males with Klinefelter's Syndrome.
- Diagnosis of Klinefelter's Syndrome is based on evidence of hypogonadism and/or infertility, plus a karyotype showing an XXY sex chromosome complement.