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Incapacity (Noun)

Lack of physical or natural qualifications.

Nouns denoting attributes of people and objects.

The doctor's old age and increasing frailty led to her eventual retirement due to a lack of physical capacity for her demanding job.
His lack of natural aptitude for the piano made him question whether pursuing music as a career was worthwhile.
She eventually quit her job as a nurse due to a physical incapacity that prevented her from lifting heavy patients.
His speech impediment and stuttering meant he struggled to effectively communicate, putting him at a disadvantage in public speaking roles.
A serious injury that led to permanent damage caused his incapacity as an athlete, preventing him from ever participating in competitive sports again.

Lack of intellectual power.

Nouns denoting cognitive processes and contents.

The patient's progressing illness led to a significant decline in mental ability and an increasing incapacity to make rational decisions.
After major head trauma, the accident victim suffered an impaired physical and cognitive state, indicating an overall incapacity to fulfill everyday tasks.
She did exceptionally well in math but noted her own incapacities in writing clear, concise sentences and creative writing in general.
The university's instructors took students' limitations into account and offered alternative coursework to address specific learning incapacities.
Hereditary factors contributed to his low IQ and accompanying mild intellectual incapacity, but assisted living helped him cope and support his learning process.