Hemosiderin (Noun)
Meaning
A granular brown substance composed of ferric oxide; left from the breakdown of hemoglobin; can be a sign of disturbed iron metabolism.
Classification
Nouns denoting substances.
Examples
- The presence of hemosiderin in the liver tissue suggested a diagnosis of hemochromatosis, a genetic disorder that causes excessive iron buildup.
- Histopathological examination of the tissue revealed significant deposits of hemosiderin, indicating chronic iron overload.
- The hemosiderin staining in the macrophages was a key finding that supported the diagnosis of sideroblastic anemia.
- Excessive hemosiderin accumulation in the pancreas can lead to the development of diabetes in patients with iron overload disorders.
- The pathologist's report noted the presence of hemosiderin in the bone marrow, which was consistent with the patient's history of repeat blood transfusions.