Gastrin (Noun)
Meaning
Polypeptide hormone secreted by the mucous lining of the stomach; when peptides and amino acids are present in the small intestine the secretion of gastric acid is stimulated.
Classification
Nouns denoting body parts.
Examples
- Gastrin is a peptide hormone secreted by G cells in the lining of the stomach that stimulates gastric acid secretion.
- When food containing proteins and amino acids reaches the stomach and duodenum, the hormone gastrin is released into the bloodstream.
- Secretion of gastrin leads to an increase in the secretion of gastric acid and an increase in gastric motility.
- Stimulation of the secretion of gastric acid occurs due to the gastrin being secreted from G cells and binds to CCK2 receptors on the stomach parietal cells.
- An imbalance of gastrin and the decrease of other digestive enzymes is observed in Zollinger-Ellison syndrome where an individual produces a large quantity of gastric acid.