Fanconi's Anemia (Noun)
Meaning
A rare congenital anemia characterized by pancytopenia and hypoplasia of the bone marrow.
Classification
Nouns denoting natural processes.
Examples
- Fanconi's anemia is a rare congenital disorder that affects the bone marrow's ability to produce blood cells.
- The diagnosis of Fanconi's anemia is confirmed by a chromosomal breakage test, which detects the characteristic chromosomal abnormalities.
- Patients with Fanconi's anemia are at increased risk of developing acute myeloid leukemia and other cancers due to their bone marrow dysfunction.
- Research into the genetic causes of Fanconi's anemia has led to a better understanding of the molecular mechanisms underlying this disorder.
- Hematopoietic stem cell transplantation is often the only treatment option for severe cases of Fanconi's anemia, as supportive care can only manage the symptoms temporarily.