Factor Xii (Noun)
Meaning
Coagulation factor whose deficiency results in prolongation of clotting time of venous blood.
Classification
Nouns denoting substances.
Examples
- Factor XII is a coagulation factor that plays a crucial role in the initiation of the intrinsic coagulation pathway in the body.
- Deficiency of factor XII can lead to prolongation of clotting time of venous blood, resulting in an increased risk of bleeding.
- Research has shown that factor XII is activated by contact with negatively charged surfaces, which triggers a cascade of reactions that ultimately lead to blood clotting.
- Individuals with factor XII deficiency may experience prolonged bleeding after surgery or injury, but it is often asymptomatic.
- The role of factor XII in coagulation has been extensively studied, and its deficiency has been linked to an increased risk of thrombosis and cardiovascular disease.