Cyclooxygenase-2 (Noun)
Meaning
An enzyme that makes prostaglandins that cause inflammation and pain and fever; "the beneficial effects of NSAIDs result from their ability to block Cox-2".
Classification
Nouns denoting substances.
Examples
- Cyclooxygenase-2 is an enzyme that plays a key role in the production of prostaglandins, which are pro-inflammatory mediators that contribute to pain, fever, and inflammation.
- The beneficial effects of NSAIDs result from their ability to block cyclooxygenase-2, thereby reducing the production of prostaglandins and alleviating symptoms of inflammation and pain.
- Cyclooxygenase-2 inhibitors, such as celecoxib, are a class of NSAIDs that selectively target the Cox-2 enzyme, reducing inflammation and pain without causing stomach ulcers.
- The overexpression of cyclooxygenase-2 has been implicated in various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders.
- Cyclooxygenase-2 is an enzyme that is involved in the conversion of arachidonic acid to prostaglandins, which are potent mediators of inflammation and pain.