Cyclooxygenase (Noun)
Meaning
Either of two related enzymes that control the production of prostaglandins and are blocked by aspirin.
Classification
Nouns denoting substances.
Examples
- Cyclooxygenase is an enzyme that plays a crucial role in the synthesis of prostaglandins, which are involved in pain and inflammation.
- The two isoforms of cyclooxygenase, COX-1 and COX-2, have distinct functions and are targeted by different types of nonsteroidal anti-inflammatory drugs.
- Aspirin works by inhibiting the activity of cyclooxygenase, thereby reducing the production of prostaglandins and alleviating pain and inflammation.
- Cyclooxygenase is overexpressed in many types of cancer, and its inhibition has been shown to have anti-tumor effects.
- The discovery of cyclooxygenase as a target for anti-inflammatory therapy has led to the development of a new class of drugs that are more selective and have fewer side effects.