Congenital Afibrinogenemia (Noun)
Meaning
A rare congenital disorder of blood coagulation in which no fibrinogen is found in the blood plasma.
Classification
Nouns denoting natural processes.
Examples
- Congenital afibrinogenemia is a rare congenital disorder of blood coagulation in which no fibrinogen is found in the blood plasma.
- People with congenital afibrinogenemia typically suffer from prolonged bleeding following injuries and spontaneous bleeding in muscles, joints, or organs.
- Congenital afibrinogenemia is caused by mutations in the three genes that make up fibrinogen, including fibrinogen alpha chain, fibrinogen beta chain, and fibrinogen gamma chain gene.
- In addition to frequent oral and nasal bleeding, individuals with congenital afibrinogenemia are at increased risk of intracranial hemorrhage.
- Mild trauma frequently causes prolonged bleeding in individuals with congenital afibrinogenemia, making participating in sports extremely high-risk.