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Caspase-mediated Cell Death (Noun)

Meaning

A type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival.

Classification

Nouns denoting natural phenomena.

Examples

  • Caspase-mediated cell death is a critical process in development and tissue homeostasis, allowing for the elimination of excess or damaged cells.
  • The dysregulation of caspase-mediated cell death has been implicated in various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.
  • Apoptosis, a form of caspase-mediated cell death, is characterized by a series of morphological changes, including cell shrinkage, chromatin condensation, and membrane blebbing.
  • Caspase-mediated cell death pathways are tightly regulated by a complex interplay of pro-apoptotic and anti-apoptotic signals, ensuring that cell death occurs only when necessary.
  • The study of caspase-mediated cell death has led to the development of novel therapeutic strategies aimed at modulating this process to treat diseases characterized by excessive or insufficient cell death.

Synonyms

  • Apoptosis
  • Programmed Cell Death

Hypernyms

  • Cell Death
  • Necrobiosis
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