Caspase (Noun)
Meaning
Any of a group of proteases that mediate apoptosis.
Classification
Nouns denoting substances.
Examples
- The caspase activation and execution phases are regulated by the intrinsic and extrinsic apoptosis pathways.
- Researchers found that inhibiting the caspase cascade reduced tissue damage after an ischemic stroke.
- In apoptosis, a family of caspases called the executioner caspases breaks down essential cellular proteins.
- Programmed cell death mediated by the activation of caspases can have an antiviral role.
- Expression of BCL-2 has been found to regulate caspase-8 expression levels, a relationship implicated in chronic lymphocytic leukemia.