Anergy (Noun)
Meaning 1
Inactivity and lack of energy.
Classification
Nouns denoting natural processes.
Examples
- The patient's anergy was concerning as it persisted for several weeks after the initial illness.
- His anergy that morning made him hit the snooze button repeatedly, unable to get out of bed.
- After breaking up with her partner, she experienced a period of anergy and depression.
- The long, cold winter had sapped the community of its energy, resulting in an overwhelming sense of anergy.
- The new employee's initial zeal eventually turned into anergy as the mundane tasks took their toll on his motivation.
Hypernyms
Meaning 2
Reduction or lack of an immune response to a specific antigen.
Classification
Nouns denoting natural processes.
Examples
- The anergy response in regulatory T cells serves as a crucial mechanism of immune tolerance to self-antigens.
- Chronic infections and some cancers induce anergy in T cells, which helps the pathogens or tumor cells evade the host immune system.
- Immune tolerance to allergens is often characterized by anergy in T helper 1 and T helper 2 cells.
- In some cases of autoimmune disease, the normal anergy response is disrupted, allowing the immune system to react against self-antigens.
- The specific mechanisms by which anergy is established and maintained in T cells are complex and involve a combination of genetic and environmental factors.