Acetylation (Noun)
Meaning
The process of introducing an acetyl group into a compound; "the acetylation of cyclooxygenase-2 by aspirin".
Classification
Nouns denoting natural processes.
Examples
- The acetylation of histones is a key regulatory mechanism in the control of gene expression.
- Acetylation of cyclooxygenase-2 by aspirin is a well-studied example of how a nonsteroidal anti-inflammatory drug can modulate enzyme activity.
- The process of acetylation can also occur on non-histone proteins, such as transcription factors and enzymes.
- Acetylation of the androgen receptor has been shown to enhance its transcriptional activity in certain types of cancer cells.
- The reversible nature of acetylation makes it an attractive target for the development of therapeutic agents that can modulate protein function.