Centromeric (Adjective)
Meaning
Pertaining to the dense specialized portion of a chromosome to which the spindle attaches during mitosis.
Classification
Relational adjectives (pertainyms).
Examples
- The centromeric region of the chromosome plays a crucial role in the segregation of sister chromatids during mitosis.
- Researchers used fluorescent probes to visualize the centromeric sequences in living cells.
- The centromeric heterochromatin is composed of highly repetitive DNA sequences that are important for kinetochore assembly.
- A defect in the centromeric protein complex can lead to abnormal chromosome segregation and genomic instability.
- The centromeric localization of certain proteins is essential for the proper attachment of microtubules to the kinetochore.