Monosomy (Noun)
Meaning
Chromosomal abnormality consisting of the absence of one chromosome from the normal diploid number.
Classification
Nouns denoting natural processes.
Examples
- Turner syndrome is a genetic disorder caused by a type of monosomy, where one of the X chromosomes is missing or partially missing.
- Women with Turner syndrome, a condition resulting from monosomy of the X chromosome, are often treated with growth hormone.
- Monosomy of chromosome 21 is usually incompatible with life and typically results in miscarriage.
- Complete monosomy of an autosome is not seen in live births due to severe developmental anomalies.
- In some cases of Edward's syndrome, a monosomy results in the absence of chromosome 18, which leads to developmental delays.